| 11/13/2010 | vs. Bloomsburg - -HOME - Hubert Jack Stadium | TBA |
| 11/6/2010 | at Indiana (Pa.) - -Away @ Indiana (Pa.) | TBA |
| 10/30/2010 | vs. Edinboro - -HOME - Hubert Jack Stadium | TBA |
| 10/23/2010 | at Slippery Rock - -Away @ Slippery Rock | TBA |
| 10/16/2010 | vs. Gannon (HC) - Lock Haven's 2010 Homecoming game -HOME - Hubert Jack Stadium | TBA |
| 10/9/2010 | vs. Clarion - -HOME - Hubert Jack Stadium | TBA |
| 10/2/2010 | at California (Pa.) - -Away @ California (Pa.) | TBA |
| 9/25/2010 | at Mercyhurst - -Away @ Mercyhurst | TBA |
| 9/18/2010 | vs. Kutztown - -HOME - Hubert Jack Stadium | TBA |
| 9/11/2010 | at Millersville - -Away @ Millersville | TBA |
| 9/4/2010 | at Virginia Military Institute - -Away @ Virginia Military Institute | TBA |